Autism - Wikipedia, the free encyclopedia. This article is about the classic autistic disorder. For other conditions sometimes called . Parents usually notice signs in the first two years of their child's life.
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Autism affects information processing in the brain by altering how nerve cells and their synapses connect and organize; how this occurs is not well understood. It occurs four to five times more often in boys than girls. About 1. 5% of children in the United States (one in 6. ASD as of 2. 01. 4. Other aspects, such as atypical eating, are also common but are not essential for diagnosis.
Noted autistic Temple Grandin described her inability to understand the social communication of neurotypicals, or people with normal neural development, as leaving her feeling . Autistic infants show less attention to social stimuli, smile and look at others less often, and respond less to their own name. Autistic toddlers differ more strikingly from social norms; for example, they have less eye contact and turn- taking, and do not have the ability to use simple movements to express themselves, such as pointing at things. However, they do form attachments to their primary caregivers. Making and maintaining friendships often proves to be difficult for those with autism.
For them, the quality of friendships, not the number of friends, predicts how lonely they feel. Functional friendships, such as those resulting in invitations to parties, may affect the quality of life more deeply. The limited data suggest that, in children with intellectual disability, autism is associated with aggression, destruction of property, and tantrums. In the second and third years, children with autism have less frequent and less diverse babbling, consonants, words, and word combinations; their gestures are less often integrated with words. Children with autism are less likely to make requests or share experiences, and are more likely to simply repeat others' words (echolalia). Both autistic groups performed worse than controls at complex language tasks such as figurative language, comprehension and inference.
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As people are often sized up initially from their basic language skills, these studies suggest that people speaking to autistic individuals are more likely to overestimate what their audience comprehends. This is closely associated with sameness and an independent validation has suggested combining the two factors. Selectivity is the most common problem, although eating rituals and food refusal also occur. Although some children with autism also have gastrointestinal symptoms, there is a lack of published rigorous data to support the theory that children with autism have more or different gastrointestinal symptoms than usual. However, they reported lower levels of closeness and intimacy than siblings of children with Down syndrome; siblings of individuals with ASD have greater risk of negative well- being and poorer sibling relationships as adults. Typically, autism cannot be traced to a Mendelian (single- gene) mutation or to a single chromosome abnormality, and none of the genetic syndromes associated with ASDs have been shown to selectively cause ASD.
No evidence has been found for these claims, and some such as the MMR vaccine have been completely disproven. This has led to unsupported theories blaming vaccine . How autism occurs is not well understood. Its mechanism can be divided into two areas: the pathophysiology of brain structures and processes associated with autism, and the neuropsychological linkages between brain structures and behaviors.
It is not known whether early overgrowth occurs in all children with autism. It seems to be most prominent in brain areas underlying the development of higher cognitive specialization. Children with autism have been found by researchers to have inflammation of both the peripheral and central immune systems as indicated by increased levels of pro- inflammatory cytokines and significant activation of microglia. It is thought that activation of a pregnant mother's immune system such as from environmental toxicants or infection can contribute to causing autism through causing a disruption of brain development. Also, some inborn errors of metabolism are associated with autism, but probably account for less than 5% of cases. The MNS operates when an animal performs an action or observes another animal perform the same action.
The MNS may contribute to an individual's understanding of other people by enabling the modeling of their behavior via embodied simulation of their actions, intentions, and emotions. In people with autism the two networks are not negatively correlated in time, suggesting an imbalance in toggling between the two networks, possibly reflecting a disturbance of self- referential thought. Research on autism/schizophrenia relations for chromosome 1. Hypo- connectivity seems to dominate, especially for interhemispheric and cortico- cortical functional connectivity. Simon Baron- Cohen's empathizing.
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